Juvenile Dermatomyositis: An Update

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An update in the diagnosis and management of juvenile dermatomyositis

Idiopathic inflammatory myopathies (IIM) represent a group of autoimmune muscle conditions with variable organ involvement amongst the different types [1]. Juvenile dermatomyositis (JDM) is the most prevalent subgroup among children (accounting for up to 85% of cases), while polymyositis, inclusion body myositis and dermatomyositis are most common in adults [2]. JDM is primarily a capillary vas...

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Juvenile dermatomyositis: review and update of the pathogenesis and treatment.

Juvenile dermatomyositis (JDM) is an autoimmune disease characterized by systemic vasculopathy. Its main manifestations include symmetrical proximal muscle weakness, elevated serum muscle enzymes and cutaneous lesions, among which the heliotrope and Gottron's papules are pathognomonic. Early recognition and prompt therapy allow better prognosis and prevent the development of calcinosis. Althoug...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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Juvenile Dermatomyositis: A Review

Juvenile dermatomyositis is a systemic vasculopathy, affecting mainly the skin and muscle. In the United States, it is seen in more than three per million children per year. It is diagnosed on the basis of the criteria set by Bohan and Peter. The following review describes the characteristic clinical manifestations, the pathophysiology and immunology of the disease. The various treatment modali...

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ژورنال

عنوان ژورنال: Bangladesh Journal of Child Health

سال: 1970

ISSN: 2408-8315,0257-3490

DOI: 10.3329/bjch.v33i2.5684